| Webster's Online Dictionary |
| Expressions | Domain | Definition | |
| Gene therapy | Health | 1: An experimental procedure aimed at replacing, manipulating, or supplementing nonfunctional or misfunctioning genes with healthy genes. See also: gene, inherit, somatic cell gene therapy, germ line gene therapy. (references) | |
| 2: The treatment of genetic disease accomplished by altering the genetic structure of either somatic (nonreproductive) or germline (reproductive) cells. (references) | |||
| 3: An evolving technique used to treat inherited diseases. The medical procedure involves either replacing, manipulating, or supplementing nonfunctional genes with healthy genes. (references) | |||
| 4: The introduction of new genes into cells for the purpose of treating disease by restoring or adding gene expression. Techniques include insertion of retroviral vectors, transfection, homologous recombination, and injection of new genes into the nuclei of single cell embryos. The entire gene therapy process may consist of multiple steps. The new genes may be introduced into proliferating cells in vivo (e.g., bone marrow) or in vitro (e.g., fibroblast cultures) and the modified cells transferred to the site where the gene expression is required. Gene therapy may be particularly useful for treating enzyme deficiency diseases, hemoglobinopathies, and leukemias and may also prove useful in restoring drug sensitivity, particularly for leukemia. (references) | |||
| Gene therapy | Medicine | A technique adopted to overcome genetically linked disorders or disease. Where such disorders are known to be associated with a simple incorrect base sequence in a gene, or the failure to produce a certain polypeptide, it may be possible to use gene manipulation techniques to correct this defect. This can be done by micromanipulation of ova or of embryos at an early stage of development. Source: European Union. (references) | |
| Gene therapy | Religion | Treatment that alters a gene. In studies of gene therapy for cancer, researchers are trying to improve the body's natural ability to fight the disease or to make the cancer cells more sensitive to other kinds of therapy. (references) | |
| Gene therapy (genetic therapy) | Geology | The process of introducing new genes into the DNA of a person's cells to correct a genetic disease or flaw. (references) | |
| Germ cell (germ line) gene therapy | Geology | The repair or re- placement of a defective gene within the gamete-forming tissues, which produces a heritable change in an organism's genetic constitution. (references) | |
| Germ line gene therapy | Energy | An experimental process of inserting genes into germ cells or fertilized eggs to cause a genetic change that can be passed on to offspring. May be used to alleviate effects associated with a genetic disease. See also: genomics, somatic cell gene therapy.. (references) | |
| Human gene therapy | Geology | Insertion of normal DNA directly into cells to correct a genetic defect. (references) | |
| Human gene therapy | Health | See: gene therapy. (references) | |
| Somatic cell gene therapy | Health | Incorporating new genetic material into cells for therapeutic purposes. The new genetic material cannot be passed to offspring. See also: gene therapy. (references) | |
Source: compiled by the editor from various references; see credits. | Top | ||
Topics by Level of Interest: Gene Therapy | ||||
| Topics sorted by level of Interest | Level (1=low, 600=high) | Topics sorted Alphabetically | Level (1=low, 600=high) | |
| Gene therapy | 53 | American Society of Gene Therapy | 3 | |
| Pharmacological gene therapy | 3 | Gene therapy | 53 | |
| American Society of Gene Therapy | 3 | Pharmacological gene therapy | 3 | |
Source: the editor, created by/for EVE to gauge likely levels of human interest in linguistically triggered topics (compiled across various sources, such as Wikipedia and specialty expression glosses). | ||||
